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March 1, 1995International Journal of Radiation Oncology*Biology*PhysicsOpen Access

Radiation injury to the heart

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Key result

Incidental cardiac irradiation is linked to late complications, primarily pericardial disease and accelerated CAD.

Why the study?

What are the late clinical manifestations of cardiac complications following incidental irradiation of the heart during treatment of thoracic neoplasms?

Population

Patients with thoracic neoplasms receiving incidental irradiation of the heart

Design

Review

Follow-up

months to years

Authors

JSJohn StewartBournemouth UniversityLFLuis F. FajardoUniversidad Pontificia BolivarianaSGS.M. GilletteThe University of Texas MD Anderson Cancer Center

Discussion

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Implication

Warrants cardiac shielding in thoracic radiotherapy; leaves open modern dose constraints and surveillance protocols.

Structured PICO

What are the late clinical manifestations of cardiac complications following incidental irradiation of the heart during treatment of thoracic neoplasms?

P
Population
Patients with thoracic neoplasms receiving incidental irradiation of the heart
E
Exposure
Incidental irradiation of the heart during treatment of thoracic neoplasms
O
Outcome
Clinical manifestations of cardiac complications (late effects)safety

Incidental irradiation of the heart during thoracic neoplasm treatment can lead to late cardiac complications, notably pericardial disease and accelerated coronary artery disease.

Cite This Study

Stewart et al. (1995) conducted a review in Thoracic neoplasms / radiation injury to the heart. Incidental irradiation of the heart was evaluated on Late cardiac complications. Incidental irradiation of the heart during treatment of thoracic neoplasms can lead to late cardiac complications, most commonly pericardial disease and accelerated coronary artery disease.

synapsesocial.com/papers/6aa9101d598f9870ab5130cdhttps://doi.org/10.1016/0360-3016(94)00656-6

Topics

Cardiomyopathy
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Also Consider

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  1. 1Heart Disease after Radiation1983 · 21 citations
  2. 2Late Cardiac Effects of Therapeutic Mediastinal Irradiation1983 · 181 citations
  3. 3HEART DISEASE FOLLOWING RADIATION1967 · 260 citations
  4. 4Dose Response in Human and Experimental Radiation-Induced Heart Disease1971 · 110 citations
  5. 5Adriamycin cardiotoxicity1977 · 131 citations