Key result
A respiratory difference in tricuspid regurgitation systolic velocity ≥0.6 m/s diagnosed severe TR with 66% sensitivity and 94% specificity (AUC 0.92; 95% CI 0.87-0.96; P<0.001).
Why the study?
Does excessive respiratory variation in tricuspid regurgitation systolic velocities accurately diagnose severe tricuspid regurgitation?
Population
136 patients with tricuspid regurgitation (n=68 with severe TR and n=68 with moderate TR)
Comparison
Measurement of the difference between maximal… vs Patients with moderate TR
Design
Cross-sectional
Authors
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High specificity may aid ruling in severe TR; leaves open prospective validation before clinical adoption.
Observational (n=136)
Does excessive respiratory variation in tricuspid regurgitation systolic velocities accurately diagnose severe tricuspid regurgitation?
Effect estimate: AUC 0.92 (95% CI 0.87-0.96)
Absolute Event Rate: 0.72% vs 0.28%
p-value: p=< 0.001
A respiratory difference in tricuspid regurgitation systolic velocity of ≥0.6 m/s is a highly specific echocardiographic sign for diagnosing severe tricuspid regurgitation.
Mutlak et al. (2013) conducted an observational in Tricuspid regurgitation (n=136). Respiratory changes in TR systolic velocities vs. Patients with moderate TR was evaluated on Diagnosis of severe tricuspid regurgitation (AUC 0.92, 95% CI 0.87-0.96, p=< 0.001). A respiratory difference in tricuspid regurgitation systolic velocity ≥0.6 m/s diagnosed severe TR with 66% sensitivity and 94% specificity (AUC 0.92; 95% CI 0.87-0.96; P<0.001).
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