Key result
BNP levels were significantly higher in patients with massive pulmonary embolism (130 ± 15 pg/ml) compared to mild to moderate embolism (91 ± 7 pg/ml) (P < 0.05), associating with increased mortality.
Why the study?
Does brain natriuretic peptide level predict severity and mortality in patients with acute pulmonary embolism?
Population
30 consecutive patients arriving at the emergency department with shortness of breath and moderate to high…
Design
Cohort
Authors
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May support BNP for risk stratification in acute PE; leaves open prospective validation before practice change.
Observational (n=30)
Does brain natriuretic peptide level predict severity and mortality in patients with acute pulmonary embolism?
Absolute Event Rate: 130% vs 91%
p-value: p=<0.05
Elevated BNP levels are significantly associated with massive pulmonary embolism and increased mortality, suggesting its utility as a prognostic marker in acute pulmonary embolism.
El-Habashy et al. (2014) conducted an observational in Acute pulmonary embolism (n=30). Massive pulmonary embolism vs. Mild to moderate pulmonary embolism was evaluated on Brain natriuretic peptide (BNP) levels (p=<0.05). BNP levels were significantly higher in patients with massive pulmonary embolism (130 ± 15 pg/ml) compared to mild to moderate embolism (91 ± 7 pg/ml) (P < 0.05), associating with increased mortality.
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