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January 1, 1987BJOG An International Journal of Obstetrics & Gynaecology

The effect of epidural anaesthesia for caesarean section on maternal uterine and fetal umbilical artery blood flow velocity waveforms

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Key result

Epidural anaesthesia with prior crystalloid infusion significantly decreased maternal uteroplacental and fetal umbilical artery systolic/diastolic ratios during caesarean section.

Why the study?

Does epidural bupivacaine and crystalloid infusion improve maternal uteroplacental and fetal umbilical artery blood flow resistance in normal patients undergoing elective caesarean section?

Population

8 otherwise normal patients undergoing elective lower segment caesarean section

Design

Case_series

Authors

WGWarwick GilesUniversity of SheffieldFLFrank X. LahWestmead HospitalBTBrian TrudingerThe University of Sydney

Discussion

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Implication

Should not change caesarean anaesthesia practice; leaves open whether epidural with crystalloid improves uteroplacental flow.

Study Design

Type

Observational (n=8)

Structured PICO

Does epidural bupivacaine and crystalloid infusion improve maternal uteroplacental and fetal umbilical artery blood flow resistance in normal patients undergoing elective caesarean section?

P
Population
8 normal pregnant women undergoing elective lower segment caesarean section.
E
Exposure
1 litre intravenous crystalloid infusion followed by epidural bupivacaine injection
O
Outcome
Systolic/diastolic A/B ratio (index of blood flow resistance) for the uteroplacental and fetal umbilical circulationsurrogate

Epidural anesthesia and crystalloid infusion decrease maternal uteroplacental and fetal umbilical artery blood flow resistance, suggesting improved maternal uterine perfusion.

Cite This Study

Giles et al. (1987) conducted an observational in Elective lower segment caesarean section (n=8). Intravenous crystalloid infusion and epidural bupivicaine injection was evaluated on Maternal uteroplacental and fetal umbilical artery systolic/diastolic (A/B) ratios. Epidural anaesthesia with prior crystalloid infusion significantly decreased maternal uteroplacental and fetal umbilical artery systolic/diastolic ratios during caesarean section.

synapsesocial.com/papers/6a9958471c4dac29babd6469https://doi.org/10.1111/j.1471-0528.1987.tb02253.x
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fetal circulation during epidural analgesia for caesarean section.1984 · 15 citations
  2. 2Fetal umbilical artery flow velocity waveforms and placental resistance: clinical significance1985 · 567 citations