Population
Untraumatized and unanesthetized animal preparation (microcirculation)
Design
Preclinical
Authors
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Animal microvessel data on shear-dependent leukocyte adherence; hypothesis-generating and requires human validation before clinical consideration.
Initial leukocyte adherence in microvessels depends on blood shear stress, whereas subsequent rolling velocity relates to linear blood velocity.
Harvey et al. (1977) studied this question.
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