Key result
Fowl adenovirus serotype 11 (FAdV-11) was identified as the primary causative agent of recent Inclusion Body Hepatitis outbreaks in Indian broiler chickens, showing >97% sequence homology.
Why the study?
Recent inclusion body hepatitis outbreaks in India have involved serotypes other than fowl adenovirus type 4 despite regular vaccination, prompting the isolation and molecular characterization of associated strains.
FAdV-11 is currently associated with inclusion body hepatitis outbreaks in Indian broiler chickens, causing severe mortality in experimental models.
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Multiple FAdV serotypes now drive IBH outbreaks despite vaccination; leaves open optimal serotype-specific control strategies for Indian poultry.
Shinde et al. (2020) studied Inclusion Body Hepatitis (IBH) (n=193). Fowl adenovirus (FAdV) serotype 11 was evaluated on Detection of FAdV Hexon gene and sequence homology. Fowl adenovirus serotype 11 (FAdV-11) was identified as the primary causative agent of recent Inclusion Body Hepatitis outbreaks in Indian broiler chickens, showing >97% sequence homology.
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