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A new technique has been described for the estimation of the power of a substance to accelerate the healing of bone. It has been found by this method that neither vitamin C nor calcium glucono‐galacto‐gluconate in the doses given accelerates the healing of bone in rats on an adequate diet when injected subcutaneously. On the other hand, it has been found that calcium ascorbate injected subcutaneously into rats does statistically increase the amount of bone regenerated by the end of 7 days. The vitamin C used for these experiments was Redoxon, Roche, and I am greatly indebted to Roche Products Ltd., not only for the vitamin C, but also for making the calcium ascorbate specially for this work at my request.
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Bourne et al. (1942) studied this question.
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