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Aziridination of N -sulfonyl imines with α-ketoesters in the presence of P(NMe 2 ) 3 is reported. Adducts derived from trivalent phosphorus reagents and α-ketoesters are effectively intercepted by imines, affording a range of aziridine-2-carboxylates. The diastereoselectivity of the reaction depends on steric hindrance from substituents on the substrates.
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Jiang et al. (2016) studied this question.
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