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June 30, 2022European Journal of Sport Science

How does multi‐set high‐load resistance exercise impact neuromuscular function in normoxia and hypoxia?

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Key result

Moderate normobaric hypoxia during multi-set, high-load resistance exercise increased metabolic stress but did not significantly alter neuromuscular function compared to normoxia.

Why the study?

It was unclear whether hypoxia during multi-set, high-load resistance exercise alters neuromuscular responses.

Does moderate normobaric hypoxia alter neuromuscular responses during multi-set high-load resistance exercise in resistance-trained males?

Population

Eight resistance-trained males

Comparison

Moderate normobaric hypoxia vs normoxia during resistance exercise

Design

Single-blinded randomised crossover study

Follow-up

5 min post-session

Authors

NBNat BenjanuvatraDBDuncan G. BradburyGLGrant Landers

Discussion

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Overview

Hypoxia increases metabolic stress without altering neuromuscular responses during high-load bench press; leaves open whether hypoxic training yields unique neuromuscular benefits.

Study Design

Type

RCT (n=8)

Blinding

Single-blind

Randomization

Crossover

Structured PICO

Does moderate normobaric hypoxia alter neuromuscular responses during multi-set high-load resistance exercise in resistance-trained males?

P
Population
8 resistance-trained males completing multi-set high-load bench press exercises in a randomized crossover design.
I
Intervention
Five sets of five repetitions of bench press at 80% of one repetition maximum in moderate normobaric hypoxia (inspiratory oxygen fraction = 0.145)
C
Comparator
Same exercise protocol in normoxia
O
Outcome
Neuromuscular responses including force during pre-/post-session maximal voluntary isometric contractions, bar velocity during exercise sets, and surface electromyographic (EMG) activitysurrogate

Main Result

p-value: p=0.423

Acute delivery of systemic normobaric hypoxia during high-load resistance exercise increases metabolic stress but does not significantly alter neuromuscular function.

Cite This Study

Benjanuvatra et al. (2022) conducted an RCT in Healthy (resistance-trained) (n=8). Moderate normobaric hypoxia vs. Normoxia was evaluated on Neuromuscular responses (mean bar velocity, surface EMG amplitude, peak/mean forces) (p=0.423). Moderate normobaric hypoxia during multi-set, high-load resistance exercise increased metabolic stress but did not significantly alter neuromuscular function compared to normoxia.

synapsesocial.com/papers/6a99738eb01d932fdc7c96e5https://doi.org/10.1080/17461391.2022.2095929
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Also Consider

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  1. 1Effect Size Guidelines, Sample Size Calculations, and Statistical Power in Gerontology2019 · 823 citations
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