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August 31, 2020The Journal of Strength and Conditioning ResearchOpen Access

Subjects in both groups substantially improved their calculated 1RM strength for leg extension, pectoral fly, row, and squat, but hypoxia did not augment this response compared to normoxia.

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Why the study?

The study investigated the effect of normobaric hypoxia on strength, body composition, and cardiovascular fitness following resistance training in older adults.

Does normobaric hypoxia improve strength, body composition, and cardiovascular fitness in healthy older adults undergoing resistance training?

Population

20 healthy adults aged 60-75 years

Comparison

Resistance training in normobaric hypoxia (14.4% O2) vs normoxia

Design

Single-blinded randomized control trial

Follow-up

8 weeks

Authors

GAGiselle AllsoppSHSamantha M. HoffmannSFSimon A. Feros

Discussion

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Overview

Normobaric hypoxia adds no benefit to resistance training in healthy older adults; challenges hypotheses of hypoxic augmentation.

Structured PICO

Does normobaric hypoxia improve strength, body composition, and cardiovascular fitness in healthy older adults undergoing resistance training?

P
Population
20 healthy adults aged 60-75 years
I
Intervention
8-week resistance training intervention in normobaric hypoxia (14.4% O2), performing 2 sessions per week of upper-body and lower-body exercises at 70% of 1 repetition maximum (1RM)
C
Comparator
8-week resistance training intervention in normoxia, performing 2 sessions per week of upper-body and lower-body exercises at 70% of 1 repetition maximum (1RM)
O
Outcome
Strength (calculated 1RM), body composition (fat and lean mass via DXA), and cardiovascular fitness (VO2 max, muscular endurance)surrogate

Normobaric hypoxia during resistance training does not augment strength, body composition, or cardiovascular fitness improvements in healthy older adults compared to normoxia.

Cite This Study

Allsopp et al. (2020) studied this question.

synapsesocial.com/papers/6a198df8124e01de928e006bhttps://doi.org/10.1519/jsc.0000000000003780
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of strength training under hypoxic conditions on muscle performance, body composition and haematological variables2020 · 21 citations
  2. 2Combining Normobaric Hypoxia With Short-term Resistance Training Has No Additive Beneficial Effect on Muscular Performance and Body Composition2013 · 39 citations
  3. 3Influence of Normobaric Hypoxia on Maximal Force Production Following High-Intensity Resistance Circuit Training2026
  4. 4Effects of Aerobic Exercise Training in Hypoxia Versus Normoxia on Body Composition and Metabolic Health in Overweight and/or Obese Populations: an Updated Meta-Analysis2025
  5. 5The Acute Effects of Normobaric Hypoxia on Strength, Muscular Endurance and Cognitive Function: Influence of Dose and Sex2022 · 20 citations