Key result
Severe obesity (BMI ≥40 kg/m2) significantly increased the odds of a prolonged length of stay >2 days (OR 1.58) and 30-day readmission (OR 1.54) following minimally-invasive radical prostatectomy.
Why the study?
The study sought to determine the role of body mass index on quality indicators, including length of stay and readmission, following minimally invasive radical retropubic prostatectomy.
Does obesity increase the risk of prolonged length of stay and readmission in patients undergoing minimally-invasive radical prostatectomy?
Observational (n=49,238)
Yes
Does obesity increase the risk of prolonged length of stay and readmission in patients undergoing minimally-invasive radical prostatectomy?
Odds Ratio: 1.58 (95% CI 1.35–1.84)
Absolute Event Rate: 18.4% vs 11.4%
p-value: p=<0.0001
Obesity is associated with a graded increase in the risk of prolonged length of stay and 30-day readmission following minimally-invasive radical prostatectomy.
Severe obesity was associated with higher perioperative risks after minimally invasive prostatectomy; extends observational data but leaves causal interventions open.
PURPOSE: We sought to determine the role of body mass index (BMI) on quality indicators, such as length of stay and readmission. The National Surgical Quality Improvement Program (NSQIP) database was queried to examine the effect of obesity, defined as BMI >30, on outcomes after Minimally Invasive Radical Retropubic Prostatectomy (MI-RRP). MATERIALS AND METHODS: Utilizing the NSQIP database, patient records were identified using the Current Procedural Terminology (CPT) code 55866 (laparoscopy, surgical prostatectomy, radical retropubic) during a 10-year period (2007-2017). Obesity was classified according to the CDC classification. Chi-square tests were utilized to evaluate BMI distribution by surgery year. Logistic regression was used to evaluate the relationship of BMI with length of stay (LOS) and hospital readmission within 30 days, after controlling for preoperative variables. RESULTS: Records of 49,238 patients who have undergone MI-RRP during 2007-2017 were evaluated. Mean yearly BMI rose from 28.5 to 29.2, while the percentage of surgical patients with BMI >30 rose by 5% (33% to 38%; p<0.0001) over the study period. Obese patients demonstrated higher morbidity, prolonged LOS, and increased readmission rates after MI-RRP. Obesity severity correlated negatively with quality indicators in a graded fashion. CONCLUSIONS: Obesity rates in patients undergoing MI-RRP increased from 2007-2017. Obese patients are at increased risk of morbidity, prolonged LOS, and readmission within 30 days, following MI-RRP. These patients should not be excluded from MI-RRP; rather, physicians should discuss these increased risks with their patients. Proper weight loss strategies should be instituted preoperatively to mitigate these risks.
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Pathak et al. (2021) conducted an observational in Prostate cancer (n=49,238). Severe obesity (BMI ≥40 kg/m2) vs. Non-obese (BMI <30 kg/m2) was evaluated on Length of stay > 2 days (OR 1.58, 95% CI 1.35-1.84, p=<0.0001). Severe obesity (BMI ≥40 kg/m2) significantly increased the odds of a prolonged length of stay >2 days (OR 1.58) and 30-day readmission (OR 1.54) following minimally-invasive radical prostatectomy.
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