Key result
Conscious sedation during transcatheter aortic valve replacement significantly reduced intensive care unit stay by 10.1 hours compared to general anesthesia, with no significant difference in total costs.
Why the study?
Conscious sedation has shown better clinical outcomes than general anesthesia for TAVR patients, but whether it provides any cost benefit remains unknown.
Does conscious sedation improve clinical outcomes and reduce costs compared to general anesthesia in patients undergoing TAVR?
Observational (n=418)
No
Does conscious sedation improve clinical outcomes and reduce costs compared to general anesthesia in patients undergoing TAVR?
Mean Difference: -10.1 (95% CI -12.2–-8.1)
Absolute Event Rate: 31.5% vs 41.6%
p-value: p=<0.001
Conscious sedation during TAVR is associated with shorter ICU and hospital stays compared to general anesthesia, without significantly impacting total admission costs.
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Conscious sedation was associated with shorter TAVR ICU stays at similar cost; leaves open the need for randomized confirmation before changing practice.
Ahmad et al. (2019) conducted an observational in Aortic stenosis (n=418). Conscious sedation vs. General anesthesia was evaluated on Intensive care unit (ICU) hours (MD -10.1, 95% CI -12.2 to -8.1, p=<0.001). Conscious sedation during transcatheter aortic valve replacement significantly reduced intensive care unit stay by 10.1 hours compared to general anesthesia, with no significant difference in total costs.
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