Key result
Hospitalized patients with cardiovascular diseases exhibited significant differences in body weight, BMI, lipid profile parameters, and systolic blood pressure compared to healthy controls (P<0.05).
Why the study?
Are there significant differences in lipid profiles, body weight, BMI, and blood pressure between children hospitalized with cardiovascular diseases and healthy controls?
Case-Control (n=164)
Are there significant differences in lipid profiles, body weight, BMI, and blood pressure between children hospitalized with cardiovascular diseases and healthy controls?
p-value: p=< 0.05
Children hospitalized with cardiovascular diseases exhibit significantly worse lipid profiles, higher BMI, and higher systolic blood pressure compared to healthy controls, supporting the need for early lipid monitoring.
Associated with adverse metabolic profiles in hospitalized children; hypothesis-generating and requires prospective validation before guiding practice.
Atherosclerosis is a complex condition that begins during the breastfeeding period and is influenced by lifestyle and genetic factors. The lipid profile must be carefully monitored in children belonging to risk groups, since its modifications are a factor that predicts the occurrence of cardiovascular diseases (CVD). This study aimed to make a comparative analysis of data from serial measurements of total serum cholesterol (TC) and its fractions (high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and non-HDL cholesterol) and triglycerides (TG) in patients from the cardiology unit to the data of a control group and to assess the correlations with body weight, body mass index (BMI) and blood pressure. The study cohort included 80 hospitalized patients with CVD and a control group of 84 subjects belonging to groups considered healthy. Patients with dyslipidemia were mainly from urban areas and had a family history of CVD. Significant differences (P < 0.05) were observed between the two groups in terms of body weight, BMI, TC with its fractions, TG and systolic blood pressure values. In the study group, the mean values of the lipid profile parameters were normal to high for non-HDL and TC, normal to low for HDL and high for TG. This study suggests that the lipid parameters must be carefully monitored beginning from the age of 2 years to facilitate early diagnosis of any imbalances that cause atherosclerosis and take appropriate preventive measures against related diseases that may arise from an early age.
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Bușilă et al. (2017) conducted a case-control in Cardiovascular diseases (n=164). Cardiovascular disease vs. Healthy controls was evaluated on Body weight, BMI, total cholesterol with its fractions, triglycerides, and systolic blood pressure (p=< 0.05). Hospitalized patients with cardiovascular diseases exhibited significant differences in body weight, BMI, lipid profile parameters, and systolic blood pressure compared to healthy controls (P<0.05).
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