Answers are grounded in this paper and cite their sources.
A new class of structurally rigid tricyclic amphibian chiral catalyst was rationally designed based on the hexahydropyrrolo[2,3-b]indole skeleton as a new type of chemzyme. This new type of chemzyme possesses a structurally rigid tricyclic skeleton and a chiral pocket which provides a well-organized chiral environment for asymmetric induction, as well as a hydrophobic pocket to enable organocatalytic reactions to proceed smoothly both in organic solvents and in water.
No takes yet. Share an insight, caveat, or question.
Xiao et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: