Key result
Advancing gestation in normal pregnancy was associated with a significant decrease in baseline fetal heart rate and changes in variability patterns, including rest-activity cycles after 34 weeks.
Population
59 normal pregnant patients (fetuses) between 21 and 41 weeks of gestation
Design
Cohort
Follow-up
1 hour per recording
Authors
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Establishes gestational age-specific fetal heart rate references for monitoring; leaves open outcome prediction and validation in high-risk cohorts.
Observational (n=59)
Fetal heart rate patterns evolve during normal pregnancy, with decreasing baseline rates and distinct variability changes related to gestational age and fetal activity.
Wheeler et al. (1978) conducted an observational in Normal pregnancy (n=59). Advancing gestation vs. Earlier gestation was evaluated on Baseline fetal heart rate and variability patterns. Advancing gestation in normal pregnancy was associated with a significant decrease in baseline fetal heart rate and changes in variability patterns, including rest-activity cycles after 34 weeks.
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