Key result
Anticoagulation successfully treated an incidentally detected descending aortic thrombus in a 65-year-old female, preventing subsequent complications.
Why the study?
Descending thoracic aortic mural thrombi frequently lead to distal organ and acute limb ischemia, but their formation is not fully explained and early diagnosis is challenging.
Case Report (n=1)
Anticoagulation can be a successful treatment strategy for incidentally detected descending thoracic aortic thrombus to prevent ischemic complications.
Answers are grounded in this paper and cite their sources.
May support anticoagulation for incidental descending aortic thrombus; hypothesis-generating and requires prospective validation before practice change.
Background: A mural thrombus in the descending thoracic aorta frequently leads to distal organ and acute limb ischemia, increasing overall morbidity and mortality. Early diagnosis is imperative as thrombi are usually discovered after end organ damage has taken place. The formation of a mural thrombus in descending aorta has not been fully explained; however, the principle of Virchow’s triad for thrombogenesis (hypercoagulability, stasis of blood flow and endothelial injury) remains the likely pathophysiologic mechanism.Case Presentation: We present a case of a descending aortic thrombus incidentally detected on computed tomography scan in a 65-year-old female and successfully treated with anticoagulation, preventing subsequent complications.Conclusions: Suspicion for an aortic thrombus should arise when the origin is not known for acute onset distal limb or organ ischemia.
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Khine et al. (2019) conducted a case report in Descending aortic thrombus (n=1). Anticoagulation was evaluated on Prevention of subsequent complications. Anticoagulation successfully treated an incidentally detected descending aortic thrombus in a 65-year-old female, preventing subsequent complications.
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