Key result
Medical therapy with antiplatelet, low molecular weight heparin, β-blocker, antihypertensive, and lipid-lowering drugs led to complete resolution of an aortic floating thrombus within 12 days.
Case Report (n=1)
Medical therapy with anticoagulation and antiplatelets can lead to rapid and complete resolution of an asymptomatic aortic mural thrombus in a minimally atherosclerotic vessel.
May support medical management of asymptomatic aortic thrombus; hypothesis-generating and should not yet change practice.
Aortic mural thrombi in a normal (non-aneurysmal or minimally atherosclerotic) vessel are an uncommon condition. They are usually located in the descending aorta and, less frequently, in the aortic arch or in the abdominal aorta. The typical clinical presentation is the appearance of symptoms/signs of peripheral arterial embolization, such as lower limb or visceral ischaemia, but these can also be accidentally found in asymptomatic patients. We report the case of a 40-year old man with untreated hypertension and dyslipidaemia admitted to hospital for atypical chest pain associated with an elevation in high-sensitivity troponin T with normal creatine kinase isoenzime MB creatine kinase isoenzyme. Elektrocardiogram (EKG) and transthoracic echocardiography were non-diagnostic; in order to exclude an aortic dissection, a gated chest computed tomography was performed and showed an aortic thrombus on a minimally atherosclerotic wall. Then, a transoesophageal echocardiography confirmed an aortic floating thrombus (7 × 4 mm). Cardiac surgeons advised against surgery and therapy with antiplatelet, low molecular weight heparin, β-blocker, antihypertensive and lipid-lowering drugs was initiated. A complete resolution of the thrombus was observed at the 12-day tomographic control.
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Maloberti et al. (2015) conducted a case report in Aortic mural thrombus (n=1). Medical therapy (antiplatelet, low molecular weight heparin, β-blocker, antihypertensive and lipid-lowering drugs) was evaluated on Resolution of the thrombus. Medical therapy with antiplatelet, low molecular weight heparin, β-blocker, antihypertensive, and lipid-lowering drugs led to complete resolution of an aortic floating thrombus within 12 days.
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