Key result
Systemic anticoagulation resulted in complete resolution of a large aortic mural thrombus in a patient without atherosclerotic disease, with no recurrence or complications at 1-year follow-up.
Why the study?
Aortic mural thrombus is an uncommon cause of arterial thromboembolism, particularly in patients without significant cardiovascular risk factors, and there are no clear guidelines for evaluation and treatment.
Case Report (n=1)
Systemic anticoagulation alone can lead to complete resolution of a large aortic mural thrombus in a patient without atherosclerotic disease, avoiding the need for surgical intervention.
Systemic anticoagulation may resolve aortic mural thrombus without surgery; single case leaves open need for prospective validation before practice change.
Aortic mural thrombus (AMT) is an uncommon cause of arterial thromboembolism. It is very rare in patients without significant cardiovascular risk factors. Many aetiologies can cause AMT, but there are no clear guidelines for the evaluation and treatment. We present the case of a 43-year-old woman without arteriosclerotic disease who was admitted to the hospital with peripheral embolisation from the mural thrombus in the distal arch of the aorta. Therapy with systemic anticoagulation resulted in complete resolution without necessitating any surgical or endovascular interventions. There were no reported recurrence or complications of the intra-aortic thrombus within 1-year surveillance imaging study.
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Uddin et al. (2021) conducted a case report in Aortic mural thrombus (n=1). Systemic anticoagulation (enoxaparin followed by rivaroxaban) was evaluated on Thrombus resolution and recurrence. Systemic anticoagulation resulted in complete resolution of a large aortic mural thrombus in a patient without atherosclerotic disease, with no recurrence or complications at 1-year follow-up.
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