Why the study?
Does a history of alcohol use disorder alter intrinsic brain functional connectivity patterns compared to controls?
Population
55 participants consisting of 23 patients with a history of alcohol use disorder and 32 control individuals…
Design
Case-control
Key result
A history of alcohol use disorder was associated with altered static and dynamic functional connectivity in multiple brain networks compared to controls.
Authors
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May indicate enduring network changes after alcohol use disorder; hypothesis-generating and requires longitudinal validation before any clinical use.
Observational (n=55)
Does a history of alcohol use disorder alter intrinsic brain functional connectivity patterns compared to controls?
Individuals with a history of alcohol use disorder exhibit persistent dysregulation in intrinsic brain functional connectivity networks compared to controls.
Maleki et al. (2022) conducted an observational in Alcohol use disorder (n=55). History of alcohol use disorder vs. No history of alcohol abuse was evaluated on Differences in static and dynamic intrinsic functional connectivity patterns. A history of alcohol use disorder was associated with altered static and dynamic functional connectivity in multiple brain networks compared to controls.