Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 30, 2017Cerebral CortexOpen Access

Influences of Age, Sex, and Moderate Alcohol Drinking on the Intrinsic Functional Architecture of Adolescent Brains

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does moderate alcohol drinking alter intrinsic functional network connectivity in adolescents?

Population

698 adolescents, including 581 no-to-low alcohol-consuming and 117 moderate-to-high-drinking youth.

Comparison

Moderate-to-high alcohol drinking vs No-to-low alcohol consumption

Design

Cross-sectional

Authors

EMEva M. Müller‐OehringDKDongjin KwonBNBonnie J. Nagel

Discussion

Loading...

Member takes

Overview

Adolescent alcohol use may disrupt IFN maturation; leaves open causal effects on cognition, needing longitudinal confirmation.

Structured PICO

Does moderate alcohol drinking alter intrinsic functional network connectivity in adolescents?

P
Population
698 adolescents (age 12-21 years), including 581 no-to-low alcohol-consuming and 117 moderate-to-high-drinking youth.
I
Intervention
Moderate-to-high alcohol drinking (exceeding NCANDA alcohol or drug use history criteria)
C
Comparator
No-to-low alcohol consumption (meeting basic NCANDA criteria)
O
Outcome
Intrinsic functional network (IFN) connectivity (DMN, ECN, SAN, EMN, RWN) measured by resting-state functional magnetic resonance imaging (rs-fMRI)surrogate

Moderate alcohol consumption during adolescence is associated with attenuated connectivity between emotion and default-mode networks, potentially impacting the maturation of affective and self-reflection systems.

Limitations

  • Cross-sectional design

Cite This Study

Müller‐Oehring et al. (2017) studied this question.

synapsesocial.com/papers/6a737f0220644e164b4e5e44https://doi.org/10.1093/cercor/bhx014
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Fronto‐striatal functional connectivity during response inhibition in alcohol dependence2012 · 146 citations