Key result
Conventional treatment without digoxin-specific Fab fragments appropriately managed suicidal digoxin poisoning, which was usually mild to moderate in young patients.
Why the study?
Can suicidal digoxin toxicity in young patients be successfully managed with conventional treatment without digoxin-specific Fab fragments?
Cohort (n=147)
Can suicidal digoxin toxicity in young patients be successfully managed with conventional treatment without digoxin-specific Fab fragments?
Suicidal digoxin toxicity in young patients is typically mild to moderate and can be successfully managed with conventional treatment without requiring digoxin-specific Fab fragments.
May support conventional management without Fab in mild-moderate suicidal digoxin toxicity among young patients; hypothesis-generating and should not yet change practice.
A retrospective study of 147 consecutive cases of suicidal digoxin poisoning was undertaken in order to determine the severity and outcome of toxicity without use of digoxin-specific Fab fragments. This study showed that suicidal digoxin poisoning in young patients is usually mild to moderate; even underlying cardiac disease and chronic use of digoxin has no effect on the severity of toxicity and incidence of lethal dysrhythmia in these cases. This type of toxicity responds appropriately to conventional treatment.
No takes yet. Share an insight, caveat, or question.
Sanaei‐Zadeh et al. (2011) conducted a cohort in Suicidal digoxin poisoning (n=147). Conventional treatment without digoxin-specific Fab fragments was evaluated on Severity and outcome of toxicity. Conventional treatment without digoxin-specific Fab fragments appropriately managed suicidal digoxin poisoning, which was usually mild to moderate in young patients.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: