Why the study?
Does pharmacological therapy reduce the growth of abdominal aortic aneurysms in patients with AAA?
Population
Patients with abdominal aortic aneurysm (AAA)
Design
Review
Key result
Pharmacological therapies such as doxycycline, roxithromycin, and statins show promise in limiting abdominal aortic aneurysm growth, but large randomized trials are required to confirm efficacy.
Authors
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Current evidence insufficient to guide AAA pharmacotherapy; leaves open efficacy of doxycycline, roxithromycin, and statins pending large RCTs.
Does pharmacological therapy reduce the growth of abdominal aortic aneurysms in patients with AAA?
While surgical repair is standard for large AAAs, pharmacological therapies and smoking cessation show promise for limiting the growth of small aneurysms, pending validation in large randomized trials.
Ahmed N Assar (2009) conducted a review in Abdominal aortic aneurysm. Pharmacological therapy (doxycycline, roxithromycin, statins) was evaluated. Pharmacological therapies such as doxycycline, roxithromycin, and statins show promise in limiting abdominal aortic aneurysm growth, but large randomized trials are required to confirm efficacy.