October 23, 2014VASA

Treatment with statins reduces cardiovascular mortality and slows the rate of AAA growth, whereas beta-blockers, ACE inhibitors, and AT1-receptor antagonists do not affect AAA growth.

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Population

Patients with abdominal aortic aneurysms (AAA)

Design

Review

Authors

NWNorbert Weiss RRRoman N. Rodionov AMAdrian Mahlmann

Discussion

Member takes

Overview

Supports statin use for CV risk reduction in AAA; leaves open causal effects on growth pending randomized data.

Structured PICO

Population

Patients with abdominal aortic aneurysms (AAA)

Intervention

Medical management including statins, beta-blockers, ACE inhibitors, AT1-receptor antagonists, roxithromycin, and lifestyle modification

Outcome

Cardiovascular mortality and AAA growth/progression

Patients with AAA are at high cardiovascular risk and benefit from statin therapy to reduce cardiovascular mortality and slow aneurysm growth, while other antihypertensives do not affect growth.

Cite This Study

Weiss et al. (2014) studied this question.

synapsesocial.com/papers/6a908a5ce73a4c404fc94b51 https://doi.org/10.1024/0301-1526/a000388

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October 23, 2014VASA

Treatment with statins reduces cardiovascular mortality and slows the rate of AAA growth, whereas beta-blockers, ACE inhibitors, and AT1-receptor antagonists do not affect AAA growth.

View Full Paper

Ask AI

Bookmark

Population

Patients with abdominal aortic aneurysms (AAA)

Design

Review

Authors

NWNorbert Weiss RRRoman N. Rodionov AMAdrian Mahlmann

Discussion

Member takes

Overview

Supports statin use for CV risk reduction in AAA; leaves open causal effects on growth pending randomized data.

Structured PICO

Population

Patients with abdominal aortic aneurysms (AAA)

Intervention

Medical management including statins, beta-blockers, ACE inhibitors, AT1-receptor antagonists, roxithromycin, and lifestyle modification

Outcome

Cardiovascular mortality and AAA growth/progression

Patients with AAA are at high cardiovascular risk and benefit from statin therapy to reduce cardiovascular mortality and slow aneurysm growth, while other antihypertensives do not affect growth.

Cite This Study

Weiss et al. (2014) studied this question.

synapsesocial.com/papers/6a908a5ce73a4c404fc94b51 https://doi.org/10.1024/0301-1526/a000388

Also Consider

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