Key result
Prior percutaneous transluminal angioplasty significantly increased the risk of progression to significant stenosis in PTFE grafts with borderline lesions (RR 1.91; 95% CI 1.27-2.88; P=0.002).
Why the study?
Is a watch-and-wait strategy safe for borderline asymptomatic stenoses in vascular accesses with PTFE grafts?
Population
102 borderline asymptomatic stenoses in vascular accesses with PTFE grafts
Design
Cohort
Follow-up
11 +/- 6 weeks
Authors
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Prior PTA was associated with accelerated progression in borderline PTFE lesions; supports short-term watch-and-wait yet leaves open long-term safety.
Cohort (n=102)
Is a watch-and-wait strategy safe for borderline asymptomatic stenoses in vascular accesses with PTFE grafts?
Relative Risk: 1.91 (95% CI 1.27–2.88)
p-value: p=0.002
Delaying PTA for borderline asymptomatic stenoses in PTFE grafts is safe in the short term, though prior PTA and female gender increase the risk of progression.
Tuka et al. (2009) conducted a cohort in Borderline asymptomatic stenoses in vascular accesses with PTFE grafts (n=102). Prior percutaneous transluminal angioplasty (PTA) vs. No prior PTA was evaluated on Progression to significant stenosis (RR 1.91, 95% CI 1.27-2.88, p=0.002). Prior percutaneous transluminal angioplasty significantly increased the risk of progression to significant stenosis in PTFE grafts with borderline lesions (RR 1.91; 95% CI 1.27-2.88; P=0.002).
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