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April 17, 2013Journal of Medical Virology

Distribution of rotavirus G and P genotypes approximately two years following the introduction of rotavirus vaccines in South Korea

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Key result

Approximately 2 years following rotavirus vaccine introduction in South Korea, the predominant genotypes among 299 rotavirus-positive children were G1 (51.5%) and P[8] (72.6%).

Population

745 children with acute diarrhea in three provinces in South Korea (299 rotavirus-positive samples)

Design

Cross-sectional

Authors

JSJung Ok ShimVTVan Thai ThanEREell Ryoo

Discussion

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Member takes

Overview

G1/P[8] predominance persists early post-vaccination; extends surveillance data but leaves open longer-term strain shifts.

Study Design

Type

Observational (n=745)

Multicenter

Yes

Structured PICO

P
Population
745 children with acute diarrhea in South Korea, yielding 299 rotavirus-positive samples for genotyping approximately 2 years post-vaccine introduction.
O
Outcome
Prevalence of rotavirus G and P genotypes

Following the introduction of rotavirus vaccines in South Korea, G1 and P[8] remained the predominant rotavirus genotypes among children with acute diarrhea.

Cite This Study

Shim et al. (2013) conducted an observational in acute diarrhea (n=745). Rotavirus vaccines introduction was evaluated on Prevalence of rotavirus G and P genotypes. Approximately 2 years following rotavirus vaccine introduction in South Korea, the predominant genotypes among 299 rotavirus-positive children were G1 (51.5%) and P[8] (72.6%).

synapsesocial.com/papers/6a99c877a2ec1cee3d4d2301https://doi.org/10.1002/jmv.23586
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Detection of unusual rotavirus genotypes G8P[8] and G12P[6] in South Korea2007 · 56 citations
  2. 2Predominance of Rotavirus Genotype G9 during the 1999, 2000, and 2002 Seasons among Hospitalized Children in the City of Salvador, Bahia, Brazil: Implications for Future Vaccine Strategies2005 · 77 citations
  3. 3Importance of rotavirus and adenovirus types 40 and 41 in acute gastroenteritis in Korean children1990 · 64 citations
  4. 4Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens1990 · 1,581 citations
  5. 5Identification of group A rotavirus gene 4 types by polymerase chain reaction1992 · 1,408 citations