Key result
Pulmonary oedema (OR 11; 95% CI 2.3-52) and arrhythmias (OR 16.9; 95% CI 2.5-113) significantly increased the risk of adverse outcomes in pregnant women with cardiac disease.
Why the study?
Cardiac disease is a life-threatening complication during pregnancy frequently seen in resource-limited areas that often results in premature death, prompting this study to identify factors related to adverse maternal and neonatal outcomes in low-resource settings.
Cohort (n=91)
Odds Ratio: 11 (95% CI 2.3–52)
p-value: p=0.002
In pregnant women with cardiac disease in low-resource settings, pulmonary edema, arrhythmias, and limited access to care are significant risk factors for adverse maternal and neonatal outcomes.
Signals elevated maternal risk from pulmonary oedema and arrhythmias; supports closer surveillance but leaves open whether intervention changes outcomes.
Background: Cardiac disease is an important life-threatening complication during pregnancy. It is frequently seen in pregnant women living in resource-limited areas and often results in premature death. Aim: The aim of this hospital-based longitudinal study was to identify factors related to adverse maternal and neonatal outcomes in pregnant women with cardiac disease in low-resource settings. Methods: The study enrolled 91 pregnant women with congenital or acquired cardiac disease over a period of 2 years in Kenya. Results: Maternal and early neonatal deaths occurred in 12.2% and 12.6% of cases, respectively. The risk of adverse outcomes was significantly increased in those with pulmonary oedema (OR 11, 95% CI [2.3–52]; p=0.002) and arrhythmias (OR 16.9, 95% CI [2.5–113]; p=0.004). Limited access to care was significantly associated with adverse maternal outcomes (p≤0.001). Conclusion: Many factors contribute to adverse maternal and neonatal outcomes in pregnant women with cardiac disease. Access to comprehensive specialised care may help reduce cardiac-related complications during pregnancy.
No takes yet. Share an insight, caveat, or question.
Amubuomombe et al. (2020) conducted a cohort in Cardiac disease in pregnancy (n=91). Pulmonary oedema was evaluated on Adverse maternal and neonatal outcomes (OR 11, 95% CI 2.3-52, p=0.002). Pulmonary oedema (OR 11; 95% CI 2.3-52) and arrhythmias (OR 16.9; 95% CI 2.5-113) significantly increased the risk of adverse outcomes in pregnant women with cardiac disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: