Key result
Anticardiolipin antibodies were highly prevalent (87%) in children with systemic lupus erythematosus, and high levels of IgG ACLs were associated with central nervous system involvement.
Cross-Sectional (n=30)
No
In pediatric SLE, anticardiolipin antibodies are highly prevalent and associated with CNS involvement, but have low predictive value for vascular thrombosis.
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Anticardiolipin antibodies may flag CNS involvement in pediatric SLE; leaves open prospective validation for thrombosis risk stratification.
Angelo Ravelli (1994) conducted a cross-sectional in Systemic lupus erythematosus (n=30). Anticardiolipin antibodies was evaluated on Prevalence of anticardiolipin antibodies. Anticardiolipin antibodies were highly prevalent (87%) in children with systemic lupus erythematosus, and high levels of IgG ACLs were associated with central nervous system involvement.
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