Key result
Pulmonary venous and arterial compliance decreased as cardiac functional capacity deteriorated in patients with mitral stenosis, with venous compliance inversely related to internal pressure.
Why the study?
How does the compliance of the pulmonary venous and arterial systems change with worsening mitral stenosis, and what is the effect of sublingual nitroglycerin?
Population
31 subjects, including 6 control cases and 25 patients with mitral stenosis
Comparison
Sublingual nitroglycerin vs Control subjects and pre-intervention baseline
Design
Cross-sectional
Authors
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Reduced compliance tracks functional decline in mitral stenosis; extends hemodynamic observations but leaves therapeutic implications open.
Observational (n=31)
How does the compliance of the pulmonary venous and arterial systems change with worsening mitral stenosis, and what is the effect of sublingual nitroglycerin?
Pulmonary venous and arterial compliance decrease as cardiac functional capacity deteriorates in patients with mitral stenosis, and this compliance is inversely related to mean pulmonary artery wedge pressure.
Tanaka et al. (1986) conducted an observational in Mitral stenosis (n=31). Mitral stenosis vs. Control cases was evaluated on Compliance of the pulmonary venous system (Cp'v') and pulmonary arterial system (Cpa). Pulmonary venous and arterial compliance decreased as cardiac functional capacity deteriorated in patients with mitral stenosis, with venous compliance inversely related to internal pressure.
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