Key result
A low cardiac function index (<4.2 min-1) was independently associated with an increased risk of delayed cerebral ischemia (OR 2.14) and poor 3-month functional outcome in patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage.
Why the study?
Does transpulmonary thermodilution-derived cardiac function index and extravascular lung water index predict delayed cerebral ischemia and poor functional outcome in patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage?
Population
46 consecutive postoperative subarachnoid hemorrhage patients who developed Takotsubo cardiomyopathy…
Design
Cohort
Follow-up
3 months
Authors
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May support cardiac function index monitoring for DCI risk stratification in SAH-Takotsubo; hypothesis-generating, needs prospective validation before practice change.
Observational (n=46)
Yes
Does transpulmonary thermodilution-derived cardiac function index and extravascular lung water index predict delayed cerebral ischemia and poor functional outcome in patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage?
Odds Ratio: 2.14 (95% CI 1.33–2.86)
p-value: p=0.004
Prolonged low cardiac function index and pulmonary edema detected by transpulmonary thermodilution predict delayed cerebral ischemia and poor 3-month functional outcome in SAH patients with Takotsubo cardiomyopathy.
Mutoh et al. (2014) conducted an observational in Takotsubo cardiomyopathy after subarachnoid hemorrhage (n=46). Low cardiac function index (CFI < 4.2 min-1) vs. Normal cardiac function index (CFI ≥ 4.2 min-1) was evaluated on Delayed cerebral ischemia (DCI) (OR 2.14, 95% CI 1.33-2.86, p=0.004). A low cardiac function index (<4.2 min-1) was independently associated with an increased risk of delayed cerebral ischemia (OR 2.14) and poor 3-month functional outcome in patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage.
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