Key result
Conditioning of less than 8 miles on alternate days led to the most marked increases in serum CK (98-294%) and myoglobin (52-405%) after a 14-mile severe exercise test run.
Why the study?
Does physical conditioning reduce exertional rhabdomyolysis after severe exercise in well-conditioned men?
Population
15 well-conditioned men
Comparison
Conditioning by running 4 or 8 miles on… vs No conditioning
Design
RCT, Randomly divided into three conditioning groups
Follow-up
1 month
Authors
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Insufficient conditioning heightens exertional rhabdomyolysis risk after severe exercise; confirms protective role of higher training volumes in well-conditioned men.
RCT (n=15)
Randomized
Does physical conditioning reduce exertional rhabdomyolysis after severe exercise in well-conditioned men?
Higher levels of physical conditioning (8 miles on alternate days) may prevent significant exertional rhabdomyolysis after severe exercise compared to lower levels.
Maxwell et al. (2017) conducted an RCT in Exertional rhabdomyolysis (n=15). Running conditioning vs. 0 miles on alternate days was evaluated on Serum creatine kinase (CK) and myoglobin levels. Conditioning of less than 8 miles on alternate days led to the most marked increases in serum CK (98-294%) and myoglobin (52-405%) after a 14-mile severe exercise test run.
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