Key result
Liver cirrhosis was associated with significantly higher in-hospital mortality compared to no cirrhosis in patients undergoing percutaneous coronary intervention (OR 1.56) or coronary artery bypass grafting (OR 2.34) for acute coronary syndrome.
Why the study?
Data on coronary revascularization in patients with cirrhosis are scarce, and it is unknown whether patients with cardiac cirrhosis have a worse prognosis.
Does liver cirrhosis increase in-hospital mortality and morbidity in patients undergoing PCI or CABG for acute coronary syndrome?
Population
1,069,730 PCIs and 273,715 CABGs performed for ACS
Comparison
Liver cirrhosis (cardiac vs noncardiac) vs no liver cirrhosis
Design
Propensity score-matched retrospective database study
Authors
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Cirrhosis warrants heightened periprocedural caution in ACS revascularization; leaves open whether targeted strategies improve outcomes.
Observational (n=1,343,445)
Yes
Does liver cirrhosis increase in-hospital mortality and morbidity in patients undergoing PCI or CABG for acute coronary syndrome?
Odds Ratio: 1.56 (95% CI 1.1–2.25)
p-value: p=0.01
Liver cirrhosis, particularly cardiac cirrhosis, is associated with significantly higher in-hospital mortality and periprocedural morbidities in patients undergoing coronary revascularization for acute coronary syndrome.
Park et al. (2022) conducted an observational in Acute coronary syndrome requiring coronary revascularization (n=1,343,445). Liver cirrhosis vs. No cirrhosis was evaluated on In-hospital mortality (PCI cohort) (OR 1.56, 95% CI 1.10-2.25, p=0.01). Liver cirrhosis was associated with significantly higher in-hospital mortality compared to no cirrhosis in patients undergoing percutaneous coronary intervention (OR 1.56) or coronary artery bypass grafting (OR 2.34) for acute coronary syndrome.
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