Key result
Liver cirrhosis and portal hypertension were associated with significantly higher in-hospital mortality following colorectal surgery compared to no cirrhosis (14% and 29% vs. 5%, P<0.0001).
Why the study?
Does liver cirrhosis and portal hypertension increase in-hospital mortality in patients undergoing colorectal surgery?
Population
Patients who underwent colorectal surgery in the United States in the Nationwide Inpatient Sample (1998-2005)
Comparison
Liver cirrhosis and portal hypertension (exposure) vs No cirrhosis
Design
Cohort
Follow-up
in-hospital
Authors
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Patients with cirrhosis and portal hypertension may require tailored perioperative strategies for colorectal surgery; leaves open prospective validation of risk models.
Cohort
Yes
Does liver cirrhosis and portal hypertension increase in-hospital mortality in patients undergoing colorectal surgery?
Absolute Event Rate: 14% vs 5%
p-value: p=<0.0001
Liver cirrhosis, especially with portal hypertension, significantly increases in-hospital mortality and morbidity following colorectal surgery.
Nguyen et al. (2009) conducted a cohort in Colorectal surgery. Liver cirrhosis and portal hypertension vs. No cirrhosis was evaluated on In-hospital mortality (p=<0.0001). Liver cirrhosis and portal hypertension were associated with significantly higher in-hospital mortality following colorectal surgery compared to no cirrhosis (14% and 29% vs. 5%, P<0.0001).
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