Key result
Transcatheter aortic valve replacement using the self-expanding Acurate Neo2 valve was successfully performed in an 80-year-old woman with a severely calcified small aortic annulus, resulting in excellent valve hemodynamics.
Why the study?
Small aortic annulus presents a major challenge in aortic valve replacement because of increased surgical risk and higher risk of prosthesis-patient mismatch.
Case Report (n=1)
No
TAVR using the self-expanding Acurate Neo2 valve is feasible and can result in successful outcomes in patients with extremely small aortic annuli.
Answers are grounded in this paper and cite their sources.
May support TAVR feasibility in small annuli; hypothesis-generating and requires larger prospective validation.
Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesis-patient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement. We present the case of an 80-year-old woman with a small aortic annulus who underwent TAVR using a self-expanding transcatheter heart valve Acurate Neo2 after an non-ST-segment elevation myocardial infarction (NSTEMI) presentation. These risks, combined with advanced age, significant co-morbidities, and a severely calcified small aortic annulus, supported the choice of TAVR with a self-expanding Acurate Neo2 valve. Despite multiple risk factors for PPM, the patient had a successful outcome without major complications. Our case highlights the off-label use of the Acurate Neo2 valve in one of the smallest aortic annuli reported to date, showcasing its feasibility in Asian and resource-limited settings.
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Malik et al. (2025) conducted a case report in Severe aortic stenosis with small aortic annulus (n=1). Transcatheter aortic valve replacement using Acurate Neo2 was evaluated on Procedural success and valve hemodynamics. Transcatheter aortic valve replacement using the self-expanding Acurate Neo2 valve was successfully performed in an 80-year-old woman with a severely calcified small aortic annulus, resulting in excellent valve hemodynamics.
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