Why the study?
Nodular pseudoangiomatous stromal hyperplasia is a rare, poorly understood benign breast lesion, and additional reported cases are needed to develop management guidelines.
Case Report (n=1)
Histopathological testing is essential for confirming the rare diagnosis of nodular PASH and ruling out low-grade angiosarcoma.
Histopathology remains essential to exclude angiosarcoma in nodular breast lesions; single case leaves open need for larger series on PASH outcomes.
Pseudoangiomatous stromal hyperplasia (PASH) is a benign mesenchymal proliferative breast lesion. PASH seldom forms a nodule on its own, in the absence of other breast tumours, resulting in "nodular PASH." Given its rarity, we provide a fascinating case of this poorly understood breast pathology in a 25-year-old woman who was first diagnosed with fibroadenoma of the left breast. Breast ultrasonography and mammography are the most commonly used procedures for evaluating breast diseases. Fibroadenomas can have the same clinical and radiological presentation as nodular PASH. Because of the non-specific features of nodular PASH, histopathological testing remains the gold standard for confirming this unusual diagnosis and ruling out low-grade angiosarcoma. Patients with nodular PASH have a great prognosis following excision. PASH is a benign stromal growth that histologically induces a vascular lesion; additional instances must be reported in order to generate thorough guidelines for managing it.
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Swarnkar et al. (2025) conducted a case report in Pseudoangiomatous Stromal Hyperplasia (PASH) / Bilateral duct ectasia (n=1). Bilateral microdochectomy was evaluated on Symptom resolution and recurrence.
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