The impact of antibiotic therapy on the increase of resistance to Pseudomonas aeruginosa and Acinetobacter baumannii carbapenems and a discussion on the results of introducing hospital antibiotic policy regulations

In recent times, antibiotic resistance of microorganisms has become a serious problem. Many Polish hospitals lack any regulations of hospital antibiotic policy, which often results in irrational implementation of antibiotic therapy, the increase of infections caused by multi-resistant strains, high therapy costs and the dissatisfaction of the patient. In the present study, the analysis of the correlations between the use of carbapenem antibiotics among the isolated strains of the non-fermenting Gram-negative bacteria and the effectiveness of the application of the basic principles of the regulations of Hospital Antibiotic Policy in restricting the increase of resistance is discussed.