Key result
Resting global longitudinal strain was significantly impaired as myocardial perfusion abnormality severity increased (-17.9% normal, -16.8% mild/moderate, -14.2% severe; P<0.001).
Why the study?
This study aimed to investigate the correlation between resting GLS and myocardial perfusion parameters and evaluate whether resting GLS can predict myocardial perfusion abnormalities in patients with normal LVEF.
Does resting GLS correlate with myocardial perfusion abnormalities in patients with suspected angina pectoris and normal LVEF?
Observational (n=157)
Does resting GLS correlate with myocardial perfusion abnormalities in patients with suspected angina pectoris and normal LVEF?
Resting GLS impairment in patients with suspected angina and normal LVEF correlates with myocardial perfusion abnormalities and may aid in detecting hemodynamically significant coronary artery disease.
GLS may correlate with perfusion parameters in preserved LVEF; leaves open predictive utility pending prospective validation.
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Yamabe et al. (2022) conducted an observational in Stable angina pectoris with normal left ventricular ejection fraction (n=157). Resting left ventricular global longitudinal strain was evaluated on Myocardial perfusion abnormality severity (summed stress score) (R = 0.32, p=<.001). Resting global longitudinal strain was significantly impaired as myocardial perfusion abnormality severity increased (-17.9% normal, -16.8% mild/moderate, -14.2% severe; P<0.001).
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