Key result
Complete genome characterization of a rotavirus B strain from goat kids with enteritis revealed high nucleotide identity and shared ancestry with bovine RVB strains, suggesting inter-species transmission.
Characterization of a caprine RVB strain reveals inter-species transmission and genetic reassortment with bovine RVB strains.
May signal RVB as a caprine enteric pathogen; leaves open its primary role pending controlled studies.
Rotavirus B (RVB) has been associated with enteric disease in many animal species. An RVB strain was identified in pooled intestinal samples from Alpine caprine kids (between 2 and 3 days of age) experiencing high (>90 %) morbidity, and the complete caprine RVB genome was characterized. Histology revealed villus atrophy, the samples tested positive for RVB by real-time RT-PCR and metagenomic next-generation sequencing identified only RVB and orf virus. In the VP4 gene segment, the caprine RVB strain had a higher percentage nucleotide identity to the Indian bovine RVB strains than to the Japanese bovine RVB strains, but the VP7, VP6, VP2, NSP1, NSP2 and NSP5 gene segments of the American caprine RVB strain were genetically related to the Japanese bovine RVB strains. The results indicate a lack of RVB sequences to understand reassortment or the evolutionary relationship of RVB strains from cattle and goats.
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Chen et al. (2018) studied Enteritis (n=2). Rotavirus B (RVB) infection was evaluated on Complete genome characterization and phylogenetic analysis. Complete genome characterization of a rotavirus B strain from goat kids with enteritis revealed high nucleotide identity and shared ancestry with bovine RVB strains, suggesting inter-species transmission.
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