Key result
An infant with congenital nemaline myopathy developed hypertrophic cardiomyopathy and heart failure, which was treated with beta-adrenergic and angiotensin II receptor blockers.
Case Report (n=1)
This case report describes the rare presentation and medical management of hypertrophic cardiomyopathy and heart failure in an infant with congenital nemaline myopathy.
Answers are grounded in this paper and cite their sources.
Case suggests beta-blockers and ARBs may aid rare infantile HCM with nemaline myopathy; leaves open efficacy pending controlled data.
We describe an infant with nemaline myopathy accompanied by hypertrophic cardiomyopathy. The patient required long-term, intermittent positive-pressure ventilation after birth owing to muscle weakness, and cardiac failure developed during infancy. We diagnosed hypertrophic cardiomyopathy with outflow tract obstruction, and treated the heart failure with beta-adrenergic and angiotensin II receptor blockers. We discuss the prognosis of nemaline myopathy combined with hypertrophic cardiomyopathy.
No takes yet. Share an insight, caveat, or question.
Nakajima et al. (2008) conducted a case report in Congenital Nemaline Myopathy and Hypertrophic Cardiomyopathy (n=1). Beta-adrenergic and angiotensin II receptor blockers was evaluated. An infant with congenital nemaline myopathy developed hypertrophic cardiomyopathy and heart failure, which was treated with beta-adrenergic and angiotensin II receptor blockers.
Synapse has enriched 10 related papers. Consider them for comparative context: