Key result
The coexistence of acute myocardial infarction and severe hypertrophic cardiomyopathy in a premature neonate led to rapid clinical deterioration and demise after 14 days.
Why the study?
Hypertrophic cardiomyopathy is a rare and heterogeneous disorder in newborns that can predispose to other cardiac conditions such as myocardial infarction.
Case Report (n=1)
The coexistence of acute myocardial infarction and severe hypertrophic cardiomyopathy in a premature neonate is a rare condition that may indicate a fatal outcome.
May indicate fatal outcome in premature neonates with coexisting AMI and severe HCM; leaves open optimal management strategies.
Hypertrophic cardiomyopathy (HCM) is a rare and heterogeneous disorder in newborns, which can predispose them to other cardiac conditions such as myocardial infarction (MI). This case report describes the clinical presentation of a premature infant born at 30 weeks of gestation, who developed cardiac failure due to myocardial ischemia. The newborn exhibited distal acrocyanosis and respiratory distress shortly after birth. Echocardiography revealed significant left ventricular hypercontractility and hypertrophy, along with moderate pericardial effusion, tricuspid regurgitation and mitral regurgitation. Despite treatment with furosemide and inotropes, the patient's condition deteriorated, leading to demise after 14 days. Early detection of MI in newborns with vascular complications and HCM plays a crucial role in their management. In conclusion, the coexistence of acute MI and hypertrophic cardiomyopathy may be indicative of a fatal outcome. Hypertrophic cardiomyopathy (HCM) is a rare and heterogeneous disorder in newborns, which can predispose them to other cardiac conditions such as MI. This case report describes the clinical presentation of a premature infant born at 30 weeks of gestation, who developed cardiac failure due to myocardial ischemia. The newborn exhibited distal acrocyanosis and respiratory distress after birth. Echocardiography revealed significant left ventricular hypercontractility, moderate pericardial effusion, tricuspid regurgitation and mitral regurgitation. Despite treatment, the patient's condition deteriorated, leading to demise after 14 days. Early detection of MI in newborns with vascular complications and HCM plays a crucial role in their management. In conclusion, the coexistence of acute MI and hypertrophic cardiomyopathy may be indicative of a fatal outcome.
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Ghandi et al. (2023) conducted a case report in Myocardial Infarction and Severe Hypertrophic Cardiomyopathy (n=1). Acute myocardial infarction and hypertrophic cardiomyopathy was evaluated on Clinical deterioration and demise. The coexistence of acute myocardial infarction and severe hypertrophic cardiomyopathy in a premature neonate led to rapid clinical deterioration and demise after 14 days.
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