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November 1, 2004American Journal of Hypertension

Prognostic value of home heart rate for cardiovascular mortality in the general populationThe Ohasama study

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Key result

An increase of 5 beats/min in morning home-measured resting heart rate was associated with a 17% increase in the 10-year risk of cardiovascular mortality (HR 1.17; 95% CI 1.05-1.30).

Why the study?

Does home-measured resting heart rate predict cardiovascular mortality in the general population?

Population

1780 Japanese individuals ≥40 years of age who had no significant arrhythmias

Design

Cohort

Follow-up

10 years

Authors

AHAtsushi HozawaPreventive CardiologyTOTakayoshi OhkuboPreventive CardiologyMKMasahiro KikuyaPreventive Cardiology

Discussion

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Member takes

Overview

May inform risk stratification; extends prior observations to home measurement but remains hypothesis-generating without prospective validation.

Key Points

  • To determine whether self-measured resting heart rate at home predicts the 10-year risk of cardiovascular mortality in the general population.
  • Prospective cohort study analyzing 1,780 Japanese individuals aged ≥40 years without significant arrhythmias from the Ohasama study.
  • Participants self-measured morning resting heart rate and blood pressure at home using automated monitoring devices.
  • Risk of 10-year cardiovascular mortality was estimated using Cox proportional hazards regression models adjusted for major cardiovascular risk factors and home blood pressure.
  • Each 5 beats/min increase in morning home heart rate was associated with a 17% increase in cardiovascular mortality risk (95% CI, 5% to 30%), persisting after adjustment for home blood pressure.
  • Among individuals with normal home systolic blood pressure (<135 mm Hg), a resting heart rate ≥70 beats/min conferred a higher risk of cardiovascular mortality (relative hazard 2.16; 95% CI, 1.21 to 3.85) compared to those with normal blood pressure and heart rate.

Study Design

Type

Cohort (n=1,780)

Structured PICO

Does home-measured resting heart rate predict cardiovascular mortality in the general population?

P
Population
1,780 Japanese individuals ≥40 years of age without significant arrhythmias, followed for 10 years to assess the risk of cardiovascular mortality.
E
Exposure
Home-measured resting heart rate
O
Outcome
10-year risk of cardiovascular mortalityhard clinical

Main Result

Hazard Ratio: 1.17 (95% CI 1.05–1.3)

Self-measurement of resting heart rate at home is a simple and useful method for predicting long-term cardiovascular mortality risk, independent of blood pressure.

Cite This Study

Hozawa et al. (2004) conducted a cohort in Cardiovascular risk (n=1,780). Home-measured resting heart rate vs. Lower heart rate was evaluated on Cardiovascular mortality (HR 1.17, 95% CI 1.05-1.30). An increase of 5 beats/min in morning home-measured resting heart rate was associated with a 17% increase in the 10-year risk of cardiovascular mortality (HR 1.17; 95% CI 1.05-1.30).

synapsesocial.com/papers/6a9a53f6a26cdabbb2a0b5eahttps://doi.org/10.1016/s0895-7061(04)00897-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Untitled2004 · 138 citations
  2. 2Factors Affecting Home-Measured Resting Heart Rate in the General PopulationThe Ohasama Study2005 · 21 citations
  3. 3Factors Affecting Heart Rate as Measured at Home among Treated Hypertensive Patients: The Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) Study2007 · 7 citations
  4. 4Control of home heart rate and home blood pressure levels in treated patients with hypertension: the J-HOME study2007 · 5 citations
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