What question did this study set out to answer?

To determine whether home-measured blood pressure predicts cardiovascular events and total mortality more effectively than conventional office blood pressure.

April 13, 2010HypertensionOpen Access

Home-Measured Blood Pressure Is a Stronger Predictor of Cardiovascular Risk Than Office Blood Pressure

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Why the study?

Does home-measured blood pressure predict cardiovascular events more strongly than office blood pressure in adults aged 45 to 74 years?

Population

2081 randomly selected subjects aged 45 to 74 years from a prospective nationwide study

Comparison

Home-measured blood pressure vs Office blood pressure

Design

Cohort

Follow-up

mean 6.8 years

Authors

TNTeemu NiiranenPreventive Cardiology MHMarjo-Riitta A. HänninenUniversity of Turku JJJouni K. JohanssonTurku University of Applied Sciences

Discussion

Member takes

Implication

Home BP may improve CV risk stratification beyond office readings; hypothesis-generating for targeted management pending RCTs.

Key Points

To determine whether home-measured blood pressure predicts cardiovascular events and total mortality more effectively than conventional office blood pressure.
Prospective nationwide study following 2,081 randomly selected participants aged 45 to 74 years over a mean follow-up of 6.8 years.
Baseline home and office blood pressure were measured alongside standard cardiovascular risk factors.
Primary endpoint was composite cardiovascular events (162 events) and secondary endpoint was total mortality (118 deaths), assessed using multivariable Cox proportional hazards models.
When both measurements were included simultaneously, home BP independently predicted cardiovascular events (systolic HR 1.22, 95% CI 1.09–1.37; diastolic HR 1.15, 95% CI 1.05–1.26 per 10/5 mm Hg increase), whereas office BP lost predictive significance (systolic HR 1.01, 95% CI 0.92–1.12; diastolic HR 1.06, 95% CI 0.97–1.16).
Systolic home BP was the sole blood pressure metric predictive of total mortality (HR 1.11, 95% CI 1.01–1.23 per 10 mm Hg increase).

Structured PICO

Does home-measured blood pressure predict cardiovascular events more strongly than office blood pressure in adults aged 45 to 74 years?

Population

2081 randomly selected subjects aged 45 to 74 years from a prospective nationwide study

Intervention

Home-measured blood pressure

Comparator

Office blood pressure

Outcome

Incidence of a cardiovascular event (composite of cardiovascular mortality, nonfatal myocardial infarction, nonfatal stroke, hospitalization for heart failure, percutaneous coronary intervention, or coronary artery bypass graft surgery)composite

Home-measured blood pressure is a stronger predictor of cardiovascular events and total mortality than conventional office blood pressure.

Cite This Study

Niiranen et al. (2010) studied this question.

synapsesocial.com/papers/69ff98ecb124fe5819858685 https://doi.org/10.1161/hypertensionaha.109.149336

Topics

Hypertension management Women and heart disease

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Home-Measured Blood Pressure Is a Stronger Predictor of Cardiovascular Risk Than Office Blood Pressure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Home-Measured Blood Pressure Is a Stronger Predictor of Cardiovascular Risk Than Office Blood Pressure

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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