Key result
Off-pump myocardial revascularization significantly reduced aortic cross-clamping time compared to cardioplegic arrest (89.2 vs 189.9 min; p<0.05) in patients with CAD and aortic valve lesions.
Why the study?
The study aimed to evaluate outcomes of surgical treatment in patients with combined coronary artery disease and aortic valve lesion undergoing revascularization on a beating heart versus under cardioplegic arrest.
Does myocardial revascularization on a beating heart improve operative metrics and reduce hospital stay in patients with combined coronary artery disease and aortic valve lesion compared to cardioplegic arrest?
Cohort (n=41)
Does myocardial revascularization on a beating heart improve operative metrics and reduce hospital stay in patients with combined coronary artery disease and aortic valve lesion compared to cardioplegic arrest?
Absolute Event Rate: 89.2% vs 189.9%
p-value: p=<0.05
Off-pump myocardial revascularization during simultaneous aortic valve surgery significantly reduces operative times, blood transfusion requirements, and hospital length of stay compared to traditional on-pump surgery with cardioplegic arrest.
May support off-pump techniques to limit clamp time in combined CAD-valve surgery; leaves open effects on clinical outcomes.
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Комаров et al. (2022) conducted a cohort in Coronary artery disease and concomitant aortic valve lesion (n=41). Off-pump myocardial revascularization vs. Myocardial revascularization under cardioplegic arrest was evaluated on Aortic cross-clamping time (minutes) (p=<0.05). Off-pump myocardial revascularization significantly reduced aortic cross-clamping time compared to cardioplegic arrest (89.2 vs 189.9 min; p<0.05) in patients with CAD and aortic valve lesions.
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