Key result
Volumetric left atrial measurements diagnosed left atrial enlargement in 65% of patients compared to 40% using linear measurements, identifying an earlier stage of enlargement.
Why the study?
Does volumetric left atrial measurement improve the detection of left atrial enlargement compared to linear measurement in patients undergoing routine echocardiography?
Cross-Sectional (n=168)
Does volumetric left atrial measurement improve the detection of left atrial enlargement compared to linear measurement in patients undergoing routine echocardiography?
Adopting volumetric measurements for the left atrium increases the detection of left atrial enlargement by nearly 40% compared to linear measurements, potentially identifying patients at an earlier stage of disease.
Volumetric LA assessment may detect enlargement missed by linear methods in routine echocardiography; hypothesis-generating and should not yet change practice.
AIMS: To define the change in the prevalence of reported left atrial enlargement (LAE) brought by using volumetric rather than linear measurements and to detect whether individuals with LAE that would have been missed by linear measurements represent a distinct subgroup of patients. METHODS AND RESULTS: Left atrial (LA) linear dimensions and volumes were obtained and correlated with clinical and echocardiographical variables in 168 consecutive patients (age: 69 ± 10 years) undergoing routine echocardiographic studies. LAE was diagnosed in 109 out of 168 patients (65%) by volume criteria as opposed to 68 out of 168 patients (40%) by linear dimension criteria, resulting in a 'missing rate' of 37% for the latter. Patients with LAE diagnosed by volume but not by diameter measurements had a lower left ventricular mass index (LVMI). CONCLUSION: Adopting volume measurements for the LA may result in almost 40% increase in the number of patients reported as having LAE. The lower LVMI found in these patients suggests that volume-based measurements are more sensitive and detect LAE at an earlier stage than diameter-based measurements, although the prognostic and management impact of this finding remains to be established.
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Vyas et al. (2010) conducted a cross-sectional in Patients undergoing routine echocardiography (n=168). Volumetric left atrial measurements vs. Linear left atrial measurements was evaluated on Diagnosis of left atrial enlargement (LAE). Volumetric left atrial measurements diagnosed left atrial enlargement in 65% of patients compared to 40% using linear measurements, identifying an earlier stage of enlargement.
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