Key result
Diabetes in patients undergoing elective cardiac surgery was associated with increased odds of intensive care unit readmission (OR 1.70; 95% CI 1.171-2.480; p=0.005) and other complications.
Why the study?
Although diabetes is rapidly increasing in Asia, no research had evaluated its impact on cardiac surgery outcomes in a Southeast Asian cohort.
Does diabetes increase the risk of adverse outcomes in adult patients undergoing elective cardiac surgery?
Cohort (n=2,831)
Does diabetes increase the risk of adverse outcomes in adult patients undergoing elective cardiac surgery?
In a Southeast Asian cohort, diabetes is a significant predictor of adverse outcomes following elective cardiac surgery, including increased risks of AKI, infection, and ICU readmission.
Answers are grounded in this paper and cite their sources.
Diabetes may worsen elective cardiac surgery outcomes in Southeast Asians; leaves open whether ethnicity-specific risk stratification improves prediction.
Although diabetes is rapidly increasing in Asia and has been shown to be associated with worse cardiac surgery outcomes, no research has been done to study the impact of diabetes on cardiac surgery outcomes in a Southeast Asian cohort. Hence, this study aims to delineate the predictors and impact of diabetes after cardiac surgery in a multi-ethnic Southeast Asian cohort. We analysed data from 2831 adult patients undergoing elective cardiac surgery, from 2008 to 2010 in Singapore. Diabetes was found to significantly increase the odds of intensive care unit readmission by 1.70 (95% confidence interval 1.171–2.480, p = 0.005), postoperative infection by 1.73 (95% confidence interval 1.003–2.976, p = 0.049), acute kidney injury by 1.36 (95% confidence interval 1.137–1.626, p = 0.001), postoperative hyperglycaemia by 6.00 (95% confidence interval 4.893–7.348, p < 0.001), and new need for dialysis by 1.71 (95% 1.086–5.360, p = 0.021). In conclusion, diabetes is associated with increased risk for renal dysfunction, hyperglycaemia, and infection after cardiac surgery, similar to the relative risks of diabetes patients observed in Western populations.
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Moorthy et al. (2019) conducted a cohort in Elective cardiac surgery (n=2,831). Diabetes vs. No diabetes was evaluated on Intensive care unit readmission (OR 1.70, 95% CI 1.171-2.480, p=0.005). Diabetes in patients undergoing elective cardiac surgery was associated with increased odds of intensive care unit readmission (OR 1.70; 95% CI 1.171-2.480; p=0.005) and other complications.
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