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August 2, 2019Diabetes and Vascular Disease Research

Impact of diabetes on outcomes of cardiac surgery in a multiethnic Southeast Asian population

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Why the study?

Although diabetes is rapidly increasing in Asia, no research had evaluated its impact on cardiac surgery outcomes in a Southeast Asian cohort.

Does diabetes increase the risk of adverse outcomes in adult patients undergoing elective cardiac surgery?

Population

2831 adult patients undergoing elective cardiac surgery in Singapore

Comparison

Patients with diabetes vs without diabetes

Design

Retrospective cohort study

Key result

Diabetes in patients undergoing elective cardiac surgery was associated with increased odds of intensive care unit readmission (OR 1.70; 95% CI 1.171-2.480; p=0.005) and other complications.

Authors

VMVikaesh MoorthyWLWeiling LiuSCSophia Tsong Huey Chew

Discussion

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Overview

Diabetes may worsen elective cardiac surgery outcomes in Southeast Asians; leaves open whether ethnicity-specific risk stratification improves prediction.

Study Design

Type

Cohort (n=2,831)

Structured PICO

Does diabetes increase the risk of adverse outcomes in adult patients undergoing elective cardiac surgery?

P
Population
2,831 adult patients undergoing elective cardiac surgery in Singapore between 2008 and 2010.
E
Exposure
Diabetes
C
Comparator
No diabetes
O
Outcome
Intensive care unit readmission, postoperative infection, acute kidney injury, postoperative hyperglycaemia, and new need for dialysishard clinical

Main Result

Odds Ratio: 1.7 (95% CI 1.171–2.48)

p-value: p=0.005

In a Southeast Asian cohort, diabetes is a significant predictor of adverse outcomes following elective cardiac surgery, including increased risks of AKI, infection, and ICU readmission.

Cite This Study

Moorthy et al. (2019) conducted a cohort in Elective cardiac surgery (n=2,831). Diabetes vs. No diabetes was evaluated on Intensive care unit readmission (OR 1.70, 95% CI 1.171-2.480, p=0.005). Diabetes in patients undergoing elective cardiac surgery was associated with increased odds of intensive care unit readmission (OR 1.70; 95% CI 1.171-2.480; p=0.005) and other complications.

synapsesocial.com/papers/6a9a5827cbeb9500cf45b715https://doi.org/10.1177/1479164119866380
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