Key result
Patients with significant coronary stenosis had a significantly wider mean left main coronary bifurcating angle compared to those with normal coronary arteries (87.34° vs 75.53°, P < 0.001), though this was not significant in multivariate analysis.
Why the study?
Does the left main coronary bifurcating angle (LCBA) correlate with the severity of coronary atherosclerosis in patients undergoing coronary CTA?
Cross-Sectional (n=313)
No
Does the left main coronary bifurcating angle (LCBA) correlate with the severity of coronary atherosclerosis in patients undergoing coronary CTA?
Absolute Event Rate: 87.34% vs 75.53%
p-value: p=<0.001
The left main coronary bifurcating angle is wider in patients with more severe coronary atherosclerosis, although this association may be confounded by other risk factors.
Wider LCBA associated with significant stenosis univariately but not multivariately; leaves open its independent role in CAD.
We evaluated the correlation of the left main coronary bifurcating angle (LCBA) with the severity of coronary atherosclerosis, risk factors of coronary artery disease (CAD) and the feasibility of measuring the LBCA using the axial plane. Coronary Computed tomography angiographies (CTAs) of 313 patients between Nov. 2006 and Oct. 2013 were reviewed and separated into three groups. Group I (211 patients) had significant stenosis (≥50%) of the left anterior descending coronary artery (LAD) and/or left circumflex coronary artery (LCX). Group II (62 subjects) had atherosclerosis without significant stenosis. Group III (40 subjects) had unremarkable coronary CTAs. Both Group I and II patients received conventional catheter angiography to confirm the severities of coronary stenoses. Significant differences were found among the groups with respect to risk factors, such as male gender, hypertension and body mass index. Axial plane measurement was feasible in most patients (82.1%), without significant differences among the groups. The mean LCBA was 84.7° among all patients, and significantly differed among groups I, II and III (87.34°, 81.16° and 75.53°, P < 0.001). The LCBA of group I was significantly higher than group III (P < 0.001) in univariate analysis, but insignificant in multivariate analysis (P = 0.064).
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Juan et al. (2017) conducted a cross-sectional in Coronary Artery Disease (n=313). Significant coronary stenosis vs. Normal coronary arteries was evaluated on Mean left main coronary bifurcating angle (LCBA) (p=<0.001). Patients with significant coronary stenosis had a significantly wider mean left main coronary bifurcating angle compared to those with normal coronary arteries (87.34° vs 75.53°, P < 0.001), though this was not significant in multivariate analysis.
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