Key result
Nonconvulsive status epilepticus was associated with confusion and global T-wave inversion in a 78-year-old woman.
Case Report (n=1)
Global T-wave inversion can be a cardiac manifestation of nonconvulsive status epilepticus, highlighting the importance of recognizing central nervous system causes of electrocardiographic abnormalities.
Alerts clinicians to possible CNS origins of unexplained ECG changes; extends the spectrum of nonconvulsive status epilepticus but leaves causality open.
Letters15 July 1998Global T-Wave Inversion Associated with Nonconvulsive Status EpilepticusRichard G.S. Spencer, MD, PhD, Todd S. Cox, MD, and Peter W. Kaplan, FRCPRichard G.S. Spencer, MD, PhDNational Institutes of Health, National Institute on Aging; Baltimore, MD 21224Johns Hopkins School of Medicine; Baltimore, MD 21205, Todd S. Cox, MDNational Institutes of Health, National Institute on Aging; Baltimore, MD 21224Johns Hopkins School of Medicine; Baltimore, MD 21205, and Peter W. Kaplan, FRCPNational Institutes of Health, National Institute on Aging; Baltimore, MD 21224Johns Hopkins School of Medicine; Baltimore, MD 21205Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-129-2-199807150-00031 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Cardiac manifestations of central nervous system (CNS) abnormalities are well known. We describe a patient in nonconvulsive status epilepticus who had confusion and global T-wave changes.A 78-year-old woman presented to the emergency department for evaluation of 3 days of mental status changes. She had sustained an inferolateral myocardial infarction (MI) 3 years before presentation. Epilepsy with complex partial seizures, diagnosed 6 years previously, was controlled with phenytoin.The patient was oriented to person, place, and date but was confused and had general malaise. Physical examination results were normal; neurologic examination was without focal findings. Mini-Mental Status ...References1. Miyagawa K. Prominent elevation of the ST segment by convulsion. Chest. 1993; 104:653-4. Google Scholar2. Oppenheimer S, Norris JW. Cardiac manifestations of acute neurological lesions. In: Aminoff MJ, ed. Neurology and General Medicine. 2d ed. 1995:183-200. Google Scholar3. Walder LA, Spodick DH. Global T wave inversion. J Am Coll Cardiol. 1991; 17:1479-85. Google Scholar4. Smith KL, Hancock EW. Global T-wave inversion after a car accident. Hosp Pract. 1993; 28:55, 59. Google Scholar5. Lui CY. Acute pulmonary embolism as the cause of global T wave inversion and QT prolongation. A case report. J Electrocardiol. 1993; 26:91-5. Google Scholar Author, Article, and Disclosure InformationAuthors: Richard G.S. Spencer, MD, PhD; Todd S. Cox, MD; Peter W. Kaplan, FRCPAffiliations: National Institutes of Health, National Institute on Aging; Baltimore, MD 21224Johns Hopkins School of Medicine; Baltimore, MD 21205 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byErythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory EpilepsyRecombinant Human Erythropoietin Protects Myocardial Cells from Apoptosis via the Janus-Activated Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway in Rats with EpilepsyThe pathogenesis of reversible T-wave inversions or large upright peaked T-waves: Sympathetic T-wavesOutcome predictors for status epilepticus—what really countsSeizure-associated Takotsubo cardiomyopathyTakotsubo cardiomyopathy associated with epilepsy complicated with giant thrombusTakotsubo syndrome associated with seizures: An underestimated cause of sudden death in epilepsy?Electrolytes, Temperature, Central Nervous System Diseases, and Miscellaneous EffectsIsolated large inverted T wave in pulmonary edema due to hypertensive crisis: a novel electrocardiographic phenomenon mimicking ischemia?A case of takotsubo cardiomyopathy associated with epileptic seizure: reversible left ventricular wall motion abnormality and ST-segment elevationLarge T wave inversion and QT prolongation associated with pulmonary edema 15 July 1998Volume 129, Issue 2Page: 163-164KeywordsCreatineElectrocardiographyEpileptic seizuresLactate dehydrogenaseSaltsStatus epilepticusStrokeSubstance abuseToxicologyVascular diseases ePublished: 15 August 2000 Issue Published: 15 July 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
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Richard G. Spencer (1998) conducted a case report in Nonconvulsive status epilepticus (n=1). Nonconvulsive status epilepticus was evaluated. Nonconvulsive status epilepticus was associated with confusion and global T-wave inversion in a 78-year-old woman.
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