Key result
Decreasing delivered energy increased shock impedance by a mean of 21% (P<0.001), and unipolar configuration yielded about 40% higher impedance than triad configuration (P<0.001).
Why the study?
Do lead configuration, shock polarity, and delivered energy affect defibrillation impedance in patients undergoing transvenous defibrillator implantation?
RCT (n=25)
Random order
Do lead configuration, shock polarity, and delivered energy affect defibrillation impedance in patients undergoing transvenous defibrillator implantation?
p-value: p=<0.001
Transvenous lead configurations and delivered energy significantly influence shock impedance, which has important implications for low energy shocks used to terminate atrial fibrillation or ventricular tachycardia.
May inform low-energy shock programming in transvenous ICDs; leaves open effects on AF/VT termination success.
Shock impedance is an important determinant of defibrillation efficacy. Lead configuration, shock polarity, and delivered energy can affect shock impedance, but these variables have not been studied in active can lead systems. The present study was a prospective evaluation of 25 patients undergoing initial transvenous defibrillator implantation. In all patients, a dual coil lead and pectoral emulator were placed and three lead configurations were tested in random order: Lead (distal to proximal coil), unipolar (distal coil to can), and triad (distal coil to can + proximal coil). Shock energies of 0.1- to 15-J shock were evaluated. Impedance increased a mean of 21% as delivered energy was decreased (P < 0.001), an effect independent of lead configuration. At all delivered energies, impedances in the unipolar configuration were about 40% higher than triad, while the lead configuration was about 20% higher than triad (ps < 0.001). Polarity did not affect impedance. These results indicate that transvenous lead configurations and delivered energy, but not polarity, significantly influence shock impedance. The magnitude of the increase of impedance at low energies is independent of the shocking pathway. This effect has important implications for low energy shocks used to terminate atrial fibrillation or ventricular tachycardia.
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Olsovsky et al. (1999) conducted an RCT in Transvenous defibrillator implantation (n=25). Lead configuration and delivered energy vs. Triad configuration / higher energy was evaluated on Shock impedance (p=<0.001). Decreasing delivered energy increased shock impedance by a mean of 21% (P<0.001), and unipolar configuration yielded about 40% higher impedance than triad configuration (P<0.001).
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