Key result
Mycoplasma pneumoniae infection was associated with the development of transient acute hypertrophic cardiomyopathy in a child.
Case Report (n=1)
This case report describes a novel association between Mycoplasma pneumoniae infection and transient acute hypertrophic cardiomyopathy in a child.
May link Mycoplasma pneumoniae to transient pediatric hypertrophic cardiomyopathy; single case leaves open causality and generalizability.
Mycoplasma pneumoniae is a common acute respiratory pathogen causing atypical pneumonia, tracheobronchitis, bronchiolitis and pharyngitis. A wide spectrum of extrapulmonary Mycoplasma disease is recognized and includes various exanthems, Stevens-Johnson syndrome, arthritis, meningoencephalitis, hemolytic anemia and perimyocarditis. Complications may be seen in up to 30% of Mycoplasma infections. Cardiac involvement is uncommon and has been reported rarely in children. We report a child with M. pneumoniae pharyngitis, pneumonia and a transient acute hypertrophic cardiomyopathy which to our knowledge has not been described previously. The diagnosis was supported by the detection of M. pneumoniae deoxyribonucleic acid in nasopharyngeal aspirate fluid with the polymerase chain reaction (PCR) and positive serology for M. pneumoniae by IgM immunofluorescence and particle agglutination.
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Nissen et al. (1995) conducted a case report in Mycoplasma pneumoniae infection and acute hypertrophic cardiomyopathy (n=1). Mycoplasma pneumoniae infection was evaluated on Development of transient acute hypertrophic cardiomyopathy. Mycoplasma pneumoniae infection was associated with the development of transient acute hypertrophic cardiomyopathy in a child.
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