Key result
A 6-year-old girl with severe acute myopericarditis and pneumonia caused by Mycoplasma pneumoniae was successfully treated and discharged without sequelae after aggressive therapy including clarithromycin and intravenous immunoglobulin.
Case Report (n=1)
Severe acute myopericarditis associated with Mycoplasma pneumoniae infection in a child can be successfully managed with aggressive medical therapy including antibiotics and intravenous immunoglobulin.
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Supports consideration of clarithromycin plus IVIG in severe pediatric Mycoplasma myopericarditis; hypothesis-generating and does not yet alter practice.
Mycoplasma pneumoniae (M. pneumoniae) primarily causes respiratory tract infections in persons aged 5-20 years. Tracheobronchitis and bronchopneumonia are the most commonly recognized clinical symptoms associated with M. pneumoniae infection. Complications of this infection are unusual; in particular, cardiac involvement is very rare and is generally accompanied by pneumonia. Nonrespiratory illness can therefore involve direct invasion by M. pneumoniae or autoimmune mechanisms, as suggested by the frequency of cross reaction between human antigens and M. pneumoniae. Herein, we report a case of severe acute myopericarditis with pneumonia caused by M. pneumoniae in a healthy young child who presented with fever, lethargy, oliguria and dyspnea. She survived with aggressive therapy including clarithromycin, intravenous immunoglobulin, inotropics, and diuretics. The patient was discharged on the 19th day after admission and followed up 1 month thereafter at the outpatient clinic without sequelae.
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Park et al. (2012) conducted a case report in Acute myopericarditis associated with Mycoplasma pneumoniae infection (n=1). Clarithromycin, intravenous immunoglobulin, and supportive care was evaluated on Clinical recovery and resolution of myopericarditis. A 6-year-old girl with severe acute myopericarditis and pneumonia caused by Mycoplasma pneumoniae was successfully treated and discharged without sequelae after aggressive therapy including clarithromycin and intravenous immunoglobulin.
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