Key result
Male patients with hypertriglyceridemia had significantly lower post-heparin plasma lipoprotein lipase activity compared to normotriglyceridemic control males (4.7 vs 6.6 umol/ml/hr, p<0.001).
Population
Males and females with normal serum lipid concentrations, and male patients with hypertriglyceridaemia.
Design
Cross-sectional
Authors
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Reduced LPL activity may contribute to male hypertriglyceridemia; leaves open causality and therapeutic implications.
Cross-Sectional (n=113)
No
Absolute Event Rate: 4.7% vs 6.6%
p-value: p=<0.001
Hypertriglyceridemia is associated with reduced lipoprotein lipase activity, which inversely correlates with serum triglyceride levels.
Boberg et al. (1979) conducted a cross-sectional in Hypertriglyceridemia (n=113). Hypertriglyceridemia vs. Normotriglyceridemia was evaluated on Post-heparin plasma lipoprotein lipase (LPL) activity (umol/ml/hr) (p=<0.001). Male patients with hypertriglyceridemia had significantly lower post-heparin plasma lipoprotein lipase activity compared to normotriglyceridemic control males (4.7 vs 6.6 umol/ml/hr, p<0.001).
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